In this essay, there will be a discussion of the differences between sex, gender, sexuality, and genitals. If biological context is concerned then all of these terms are different and all of these terms have genetic differences as well. Differences between sex, gender, genitals, and sexuality The basic difference between sex and gender is that sex is nothing but a biological concept, which is perfectly based on several biological characteristics, like the differences in genitalia in female and male. On the other hand, gender can be considered as dealing with the societal, cultural and personal perceptions of sexuality. Both of these ideas are flexible enough in today’s society that the words look similar often.